A collaborative study with Harvard Medical School
DENTAL
Axiostat - 100% Chitosan Haemostatic Dressing Achieving Haemostatis and Healding of Extraction Wounds in Patients On Oral Antiplatelet Drugs
Center
- Department of oral and maxillofacial surgery, KLE VK Institute of dental science, Belgaum, Karnataka-India:
Dr. Saurabh Sharma & Dr. Tejraj P. Kale
Aim
The aim of this study was to evaluate the efficacy of Axiostat haemostatic dental dressing in achieving haemostasis post-extraction and determining its effect on pain and healing of the extraction wound, compared with control, i.e., conventional method of extraction in patients on oral antiplatelet therapy
Materials and Methods
Totally, 40 patients on oral antiplatelet drugs were included in the study and overall 80 extractions were done applying a split-mouth study design, without altering the patient’s drug regime. Extraction sites were divided into two groups: Group1-received Axiostat haemostatic dental dressing(study site), and group 2-received conventional method; pressure pack with sterile gauze under biting pressure followed by suturing if required (control site) was used to attain haemostasis.
Comparison of study and control groups with bleeding time in minutes
Comparison of study and control groups with healing scores
Result
Extraction sites treated with Axiostat haemostatic dressing achieved haemostasis faster(mean1 minute 13 seconds) compared with control sites ( mean= 14 minutes 1 second). Postoperative pain was considerably lower and significantly better healing was seen in the study group
Conclusion
Axiostat demonstrated to be an effective haemostatic agent that considerably lessens the bleeding time in patients on oral antiplatelet drugs post-extraction. In addition, it even offered minimal postoperative pain and improved healing of the extraction wound. Axiostat dental dressing (ADD) is found to be as effective in achieving haemostasis in patients on oral antiplatelet therapy
