Efficacy and Safety of Axiostat® Hemostatic Dressing in Aiding Manual Compression Closure of the Femoral Arterial Access Site in Patients Undergoing Endovascular Treatments: A Preliminary Clinical Experience in Two Centers

Publication Details:

Minici, R., Serra, R., Maglia, C., Guzzardi, G., Spinetta, M., Fontana, F., Venturini, M. and Laganà, D., 2023. Efficacy and Safety of Axiostat® Hemostatic Dressing in Aiding Manual Compression Closure of the Femoral Arterial Access Site in Patients Undergoing Endovascular Treatments: A Preliminary Clinical Experience in Two Centers. Journal of Personalized Medicine, 13(5), p.812.

Patient Details:

120 consecutive patients who had undergone endovascular procedures performed with introducer sheaths ranging from 4 Fr to 8 Fr were evaluated.

Key Findings and Data:

  • Axiostat achieved hemostasis in 92% of cases within 3–5 minutes, compared to 10–15 minutes with manual compression.
  • Zero re-bleeding incidents reported during the observation period.
  • No arterial occlusions detected, ensuring patent hemostasis.
  • Reduced post-procedure discharge time by ~40%, improving hospital workflow.
  • No adverse skin reactions or infections associated with Axiostat application.
Efficacy and Safety of Axiostat

Key Insights

  • Axiostat demonstrated superior efficacy in achieving rapid hemostasis compared to manual compression.
  • Protonated Bioadhesive Technology (PBT) of Axiostat not only reduced bleeding time but also ensured patient safety by preventing occlusions.
  • Axiostat is a viable alternative to vascular closure devices (VCDs), especially in anticoagulated patients where traditional methods may be less effective to control bleeding.
  • Its ease of application and ability to significantly shorten discharge times.
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